pf2e.fyi
From Pathfinder Treasure Vault (Remastered), which isn't enabled.

Sanguine Mutagen (Greater)

ITEM 11
Price 300 gp
Usage held in 1 hand
Bulk L
Category mutagen

Activate (manipulate)

For 1 hour you gain greatly increased blood production, filtering out contagions and boosting your endurance but causing your body to bloat with blood.

Benefit You gain a +3 item bonus to Fortitude and Reflex saves. This bonus improves to +4 when you attempt a save against an effect that has the disease trait, poison trait, or would give you the Fatigued condition.

When you roll a success on a save against a disease, poison, or effect that would give you the Fatigued condition, you get a critical success instead.

Drawback Whenever you take piercing or slashing damage, you take 1d6 bleed.

Effect: Sanguine Mutagen (Greater)

Pathfinder Treasure Vault (Remastered)ORC